Natural bioactive compounds may be used in obese patients because of their ability to\nimpact on various key mechanisms involved in the complex pathophysiological mechanisms of such\ncondition. The aim of this study was to investigate the effect of a Mangifera indica L. leaf extract (MLE)\non adipogenic di_erentiation of murine preadipocyte cells. 3T3-L1 cells were treated during their\ndi_erentiation with various concentrations of (Mangifera indica L.) leaves extract (MLE) (750, 380, 150,\n75 and 35 microg) in order to assess their lipid content, adiponectin production, expression profile of\ngenes involved in lipid metabolism, oxidative stress and inflammation................
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